Combining TMS and MRI

MRI can guide stimulation, measure its immediate effects, or assess changes after a stimulation protocol.

Before stimulation

Structural MRI supports neuronavigation. Functional imaging and connectivity can help define candidate targets in an individual brain.

During stimulation

Interleaved TMS-fMRI coordinates magnetic pulses with image acquisition to measure stimulation-evoked BOLD responses. Chronometric designs add precise timing relative to a cognitive task.

After stimulation

Task and resting-state fMRI can assess changes following stimulation. These measurements answer a different question from the acute response during TMS.

Our approach to concurrent TMS-fMRI →